Is the Ebola virus a DNA or RNA virus?
Ebolaviruses belong to the group of nonsegmented negative strand (NNS) RNA viruses. Most members of the Ebolavirus genus cause severe disease in humans.
What is the viral structure of Ebola?
Ebola virus is a highly pathogenic filovirus causing severe hemorrhagic fever with high mortality rates. It assembles heterogenous, filamentous, enveloped virus particles containing a negative-sense, single-stranded RNA genome packaged within a helical nucleocapsid (NC).
What form of viral reproduction does Ebola use?
Ebola Virus do not replicate through any kind of cell division; rather, they use a combination of host and virally encoded enzymes, alongside host cell structures, to produce multiple copies of viruses. These then self-assemble into viral macromolecular structures in the host cell.
How many genes are in the Ebola virus genome?
The 19-kb NNS RNA genome of EBOV is tightly wrapped by the nucleoprotein (NP) and contains seven genes in the order 3′ NP-VP35-VP40-GP-VP30-VP24-L 5′ (Fig. 1A).
What is RNA in Ebola?
Ebola, also known as Ebola virus disease (EVD/EBOV) and Ebola hemorrhagic fever (EHF) in the past, is a filamentous, enveloped, non-segmented, single stranded negative sense ribonucleic acid (RNA) virus [4]. The replication of Filoviridae family of viruses takes place in the cytoplasm of the host cell [6, 7].
Which virus is DNA virus?
DNA virus: A virus in which the genetic material is DNA rather than RNA. The DNA may be either double- or single-stranded. Major groups of double-stranded DNA viruses (class I viruses) include the adenoviruses, the herpes viruses, and the poxviruses.
Is Marburg an RNA virus?
Marburg virus disease (MVD) is a rare but severe hemorrhagic fever which affects both people and non-human primates. MVD is caused by the Marburg virus, a genetically unique zoonotic (or, animal-borne) RNA virus of the filovirus family.
How many proteins does Ebola encode?
seven proteins
The genome of ebola virus contains instructions for building seven proteins, which assemble with the genomic RNA to form one of the deadliest viruses.
What is the viral genome?
The viral genome is packed inside a symmetric protein capsid, composed of either a single or multiple proteins, each of them is encoding a single viral gene. Due to this symmetric structure, viruses could encode all the necessary information for constructing a large capsid using a small set of genes.