Why did they stop making nefazodone?

Why did they stop making nefazodone?

It’s important to note that the sale of Serzone, the brand medication of Nefazodone, was discontinued in 2003 in the United States due to the rare occurrence of severe liver damage.

What is nefazodone hydrochloride used for?

Nefazodone is used to treat depression. Nefazodone is in a class of medications called serotonin modulators. It works by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance.

Is nefazodone still available in 2021?

Nefazodone is now available.

What type of antidepressant is nefazodone?

SERZONE® (nefazodone hydrochloride) is an antidepressant for oral administration with a chemical structure unrelated to selective serotonin reuptake inhibitors, tricyclics, tetracyclics, or monoamine oxidase inhibitors (MAOI).

Does nefazodone help with anxiety?

In all 11 cases, nefazodone was efficacious and well tolerated in the treatment of both depressive and anxiety components. After nefazodone augmentation, the mean CGI score for combined depression and anxiety symptoms was (+/-sd) 1.52 (0.52) on a scale from 1 (very much better) to 7 (very much worse).

Is nefazodone a sedative?

Although nefazodone is mildly sedating clinically, it had no overall effect on total sleep time (or sleep efficiency) or the number of awakenings. In addition, all other aspects of sleep architecture, including the proportion of slow wave (stage 3 and 4) sleep, were unchanged after two weeks of treatment.

Does nefazodone help with sleep?

In summary, nefazodone, an effective antidepressant, decreases arousals and wakefulness during sleep and reduces light non-REM sleep. This agent does not appear to suppress REM sleep or prolong REM latency in patients who respond to treatment.

Is trazodone the same as nefazodone?

Trazodone is a sedating antidepressant without anticholinergic properties. Nefazodone is a new antidepressant that is a structural analogue of trazodone but is less sedating.

Is nefazodone same as trazodone?

Does nefazodone cause weight gain?

However, at any point during the long-term phase, significantly more SSRI-treated patients than nefazodone-treated patients showed a significant increase in body weight (17.9% vs. 8.3%; p = . 003).