What does Orthokeratosis meaning?
orthokeratotic hyperkeratosis. Definition: thickening of the stratum corneum of the epidermis (hyperkeratosis) with non-nucleated keratinocytes retained in this layer.
What is Hypergranulosis mean?
Hypergranulosis is an increased thickness of the stratum granulosum. [ from HPO]
What does acanthosis mean?
Acanthosis is term pathologists use to describe an increased number of specialized squamous cells on the surface of a tissue. Acanthosis is commonly seen in the top layer of the skin called the epidermis. Acanthosis can also be seen in the epithelium that lines the inside of the mouth and throat.
What is hyperkeratosis and acanthosis?
Acanthosis nigricans (AN) is a skin condition characterized by abnormally increased coloration (hyperpigmentation) and “velvety” thickening (hyperkeratosis) of the skin, particularly of skin fold regions, such as of the neck and groin and under the arms (axillae).
What is Orthokeratosis and Parakeratosis?
Orthokeratotic hyperkeratosis refers to the thickening of the keratin layer with preserved keratinocyte maturation, while parakeratotic hyperkeratosis shows retained nuclei as a sign of delayed maturation of keratinocytes.
What is compact Orthokeratosis?
Orthokeratosis. Orthokeratosis is the normal ‘basket weave’ appearance of the stratum corneum seen in normal skin. In acral skin (palms or soles), the stratum corneum exhibits thickening and compaction (‘compact orthokeratosis’).
What is focal Hypergranulosis?
Hypergranulosis means an increased number of cells in the granular layer of the skin. The granular layer is found near the surface in a part of the skin called the epidermis. Hypergranulosis is a non-cancerous change. The granular layer is a normal part of the skin and is usually 1 to 2 cells thick.
What causes acanthosis?
Acanthosis nigricans often occurs in people who have disorders such as ovarian cysts, underactive thyroids or problems with the adrenal glands. Certain drugs and supplements. High-dose niacin, birth control pills, prednisone and other corticosteroids may cause acanthosis nigricans.
What is acanthosis of epidermis?
Acanthosis is a thickening of the epidermis and elongation of the rete ridges due to thickening of the spinous layer +/- enlargement of rete pegs. Typical examples include chronic eczematous reactions.
What is the difference between Orthokeratosis and parakeratosis?
What is basket weave Orthokeratosis?
Basket-weave orthokeratosis refers to a thickened cornified layer whose cells are arrayed in a criss-cross fashion that resembles the pattern in a woven basket, it is the same configuration, only thickened, assumed by the stratum corneum of normal skin anywhere on the integument except for palms and soles, where …