What is NORVIR used to treat?
NORVIR® (ritonavir) oral powder is a prescription medicine that is used with other antiviral medicines to treat children with HIV-1 infection. HIV-1 is the virus that causes AIDS (Acquired Immune Deficiency Syndrome).
What is the generic name for NORVIR?
Ritonavir (Norvir) is a protease inhibitor and a booster medication. At high doses it stops the HIV virus from making copies of itself, and at low doses it raises the levels of other HIV ARVs.
What company makes NORVIR?
Ritonavir is manufactured as Norvir by AbbVie, Inc. The US Food and Drug Administration (FDA) approved ritonavir on March 1, 1996, making it the seventh U.S.-approved antiretroviral drug and the second U.S.-approved protease inhibitor (after saquinavir four months earlier).
What type of drug is Norvir?
NORVIR tablets and oral solution are prescription medicines that are used with other antiviral medicines to treat people with human immunodeficiency virus (HIV-1) infection. NORVIR oral powder is a prescription medicine that is used with other antiviral medicines to treat children with HIV-1 infection.
Why is ritonavir used as a booster?
However, the drug is recommended as an agent to boost other protease inhibitors. This is because ritonavir blocks the CYP3A4 pathway in the liver, which is involved in the metabolising of other protease inhibitors. This leads to higher blood concentrations of these drugs and their slower clearance from the body.
What drugs should not be taken with ritonavir?
Key drug interactions: You should not take ritonavir with any of the following drugs: alfuzosin, amiodarone, astemizole, bepridil, avanafil, chlorazepate, cisapride, colchicine, diazepam, dihydroergotamine, dronedarone, elbasvir/grazoprevir, ergonovine, ergotamine, estazolam, flecanaide, flurazepam, fusidic acid.
Why is lopinavir combined with ritonavir?
Lopinavir/ritonavir combines two drugs in one pill. Both drugs are from a class of drugs known as protease inhibitors. The drug ritonavir increases or ‘boosts’ the level of lopinavir. Your doctor will prescribe lopinavir/ritonavir as part of your HIV treatment, along with antiretrovirals from another class of drugs.
What is the side effects of Lopinavir and Ritonavir?
Diarrhea, headache, nausea, vomiting, stomach upset, drowsiness, dizziness, a bad taste in the mouth, and trouble sleeping may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
